Twin explosions strike southern Syrian city

BEIRUT (AP) — Syria‘s state-run news agency says two large explosions have struck the southern city of Daraa, causing multiple casualties and heavy material damage.

SANA did not immediately give further information or say what the target of Saturday’s explosions was.

The Britain-based Syrian Observatory for Human Rights says the blasts went off near a branch of the country’s Military Intelligence in Daraa.

The Observatory, which relies on a network of activists on the ground, says the explosions were followed by clashes between regime forces and rebels fighting to topple President Bashar Assad.

Middle East News Headlines – Yahoo! News

Read More..

Sony Animation preps sequel to hit “Hotel Transylvania”

NEW YORK (TheWrap.com) – Sony Pictures Animation will make a sequel to “Hotel Transylania,” one of the year’s surprise hits, a spokesman for the studio told TheWrap.

Tentatively titled “Hotel Transylvania 2,” the film is set for a 2015 release. There is no director attached at the moment. Genndy Tartakovsky, who directed the first one, will be helming Sony Pictures Animation‘s “Popeye.”

“Hotel Transylvania” opened to $ 42.5 million at the domestic box office and $ 50.6 worldwide, setting a new record for a September opening. It has grossed more than $ 250 million at the global box office so far.

Adam Sandler voiced the character of Dracula, who owns the titular five-star resort designed as a place for monsters to relax away from humans. Other monsters such as Murray the Mummy (Cee Lo Green), Frankenstein’s Monster (Kevin James) and Griffin the Invisible Man (David Spade) descend upon the hotel for the 118th birthday of Dracula‘s daughter Mavis (Selena Gomez).

Movies News Headlines – Yahoo! News

Read More..

FBI probe of Petraeus began with 'suspicious emails'

WASHINGTON (Reuters) - The FBI investigation that led to the discovery of CIA Director David Petraeus' affair with author Paula Broadwell was sparked by "suspicious emails" that initially did not contain any connection to Petraeus, U.S. law enforcement and security officials told Reuters on Saturday.

But the CIA director's name unexpectedly turned up in the course of the investigation, two officials and two other sources briefed on the matter said.

It was "an issue with two women and they stumbled across the affair with Petraeus," a U.S. government security source said.

The Washington Post reported on Saturday that the FBI probe was triggered when Broadwell sent threatening emails to an unidentified woman close to the CIA director.

The woman went to the FBI, which traced the threats to Broadwell and then uncovered explicit emails between Petraeus and Broadwell, the Post said.

Attempts by Reuters and other news media to reach Broadwell, an Army reserve offer and author of a biography of Petraeus, have not been successful.

The FBI and CIA declined comment on Saturday.

Many questions in the case remain unanswered publicly, including the identity of the second woman; the precise nature of the emails that launched the FBI investigation; and whether U.S. security was compromised in any way.

Nor is it clear why the FBI waited until Election Day to tell U.S. Director of National Intelligence James Clapper, who oversees the CIA and other intelligence agencies, about its investigation involving Petraeus.

The CIA director announced his resignation suddenly on Friday, acknowledging an extramarital affair and saying he showed "extremely poor judgment.

The developments likely ended the public career of one of the United States' most highly regarded generals, who was credited with helping pull Iraq out of civil war and led U.S. and NATO troops in Afghanistan.

Meanwhile, new details emerged on Saturday about developments in the final days leading to Petraeus' departure from atop the CIA.

Clapper was notified by the FBI on Tuesday evening about 5 p.m. - just as returns in the U.S. presidential election were about to come in - about "the situation involving Director Petraeus," a senior intelligence official said. Clapper and Petraeus then spoke that evening and the following morning.

WHITE HOUSE NOTIFIED WEDNESDAY

"Director Clapper, as a friend and a colleague and a fellow general officer, advised Director Petraeus that he should do the right thing and he should step down," the official said.

Clapper is a retired Air Force lieutenant general; Petraeus served nearly four decades in the U.S. Army.

On Wednesday, Clapper notified the National Security Council at the White House that Petraeus was considering resigning and President Barack Obama should be informed, the official said.

U.S. law enforcement and intelligence officials agreed to discuss the Petraeus matter only on condition of anonymity because of the issue's sensitivity and because it is the subject of a law enforcement investigation.

Once Petraeus' name turned up in the investigation, the importance of the FBI inquiry was immediately escalated, as investigators became concerned the CIA chief somehow might have been compromised, the law enforcement official said.

However, the official and two sources briefed on the matter said no evidence has turned up suggesting Petraeus had become vulnerable to espionage or blackmail. At this point, it appears unlikely that anyone will be charged with a crime as a result of the investigation, the official said.

The FBI investigation began fairly recently - months ago rather than years ago, when Petraeus would still have been in uniform as one of the U.S. Army's top field commanders, the official said.

Representative Peter King, Republican chairman of the House of Representatives' Homeland Security Committee, said in an interview on MSNBC the FBI was "investigating or monitoring ... the director of the CIA for four or five months."

Several officials briefed on the matter said senior officials at the Pentagon, CIA and Congress knew nothing of the FBI's investigation of Petraeus until Thursday afternoon at the earliest, and some key officials were not briefed on the details until Friday.

There is no evidence at this time that anyone at the White House had knowledge of the situation involving Petraeus prior to the U.S. presidential election on Tuesday, which saw Obama elected to a second four-year term.

Another U.S. government security source said it was not until Friday afternoon that some members of the House and Senate intelligence oversight committees were notified about Petraeus' resignation by Clapper's office.

The congressional committees were told that it was a personal issue that Petraeus had to discuss with his wife. When pressed, a representative of the Office of the Director of National Intelligence said it involved another woman.

(Writing by Warren Strobel; Additional reporting by Doug Palmer and Matt Spetalnick; Editing by Todd Eastham)

Read More..

Syria opposition bloc elects Christian as leader

DOHA, Qatar (AP) — Syria‘s main opposition group in exile has elected a Christian Paris-based former geography teacher as its new president.

George Sabra said Friday that his election as head of the Syrian National Council is a sign that the opposition is not plagued by sectarian divisions.

Sabra says the SNC‘s main demand is to receive weapons from the international community. The U.S. and some other foreign backers of rebels fighting the regime of President Bashar Assad have so far refused to send weapons for fear they can fall into the wrong hands.

Middle East News Headlines – Yahoo! News

Read More..

Frankfurt gears up for Gangnam Style at MTV awards

FRANKFURT (Reuters) – The MTV Europe Music Awards will rock Frankfurt’s Festhalle concert venue on Sunday, with Barbadian R&B singer Rihanna leading the nominations and all eyes on Korean dance sensation Psy.

Psy‘s hit “Gangnam Style“, which is up for the Best Video award, has been viewed more than 670 million times and received a record-breaking 4.9 million “likes” on Facebook since being released in mid-July.

The satirical video featuring Psy‘s horse riding-inspired dance has sparked a wave of copycat versions from Eton schoolboys to Californian lifeguards and has even caught the attention of United Nations chief Ban Ki-moon.

Psy will become the first South Korean artist to perform at the annual awards, one of the pop industry’s biggest nights outside the United States, when he takes the stage on Sunday.

German model and presenter Heidi Klum, who this year filed for divorce from singer husband Seal, will host the awards and said she had been practicing her Gangnam moves in case she gets called on to dance.

“My kids are obsessed with the song, even though it’s Korean and they have no idea what he’s talking about,” she told reporters ahead of the event.

Klum, who comes from the town of Bergisch Gladbach just two hours away from the 2012 host city, is also looking forward to some home comforts.

“I’ll be eating a lot of German food,” she said, adding jokingly that she would probably eat too much schnitzel and “gain a few pounds.”

Despite being billed as the Europe Music Awards, the vast majority of nominees are traditionally North American, and 2012 is no exception.

Alongside Psy, acts due to take the stage at the show include country singer Taylor Swift, 14-time Grammy winner Alicia Keys, the Killers and Carly Rae Jepsen.

“OLD WAYS” STILL COUNT

In a world where careers are so often launched by social media websites like YouTube, some young artists said there was still a role for more established platforms such as MTV and mainstream television.

American indie-pop band fun., who are up for three awards, hit the big time after the song “We Are Young” was featured in an advert for Chevrolet during the U.S. Superbowl.

“I don’t think that you can ever replace the impact that music videos have,” the band’s guitarist Jack Antonoff told Reuters when asked about the importance of MTV against social media channels.

“I think the more that social media takes over, the more importance you put upon the old ways.”

MTV said this week that it had become the first company to reach one million followers on Instagram, the fast-growing photo-sharing application developer.

Heading the nominations is party-loving Rihanna, with nods in six categories, including Best Song and Best Video for “We Found Love”.

Following close behind with five nominations is country star Swift, and other top nominees include Justin Bieber and Katy Perry, with four each, while Lady Gaga, who cleaned up last year with four prizes, is in the running for three awards.

Rihanna is favorite for Best Song and Best Female, according to odds offered by British bookmakers William Hill, while Gangnam Style is tipped to win Best Video.

The EMA awards were last held in Frankfurt in 2001. Last year’s awards in Belfast attracted 23 million viewers on all platforms and 158 million votes worldwide.

Following are the main nominations in 2012:

BEST SONG: Carly Rae Jepsen/Call Me Maybe; Rihanna feat. Calvin Harris/We Found Love; Gotye/Somebody That I Used To Know; Pitbull feat. Chris Brown/International Love; fun. feat. Janelle Monáe/We Are Young

BEST NEW: Rita Ora; fun.; One Direction; Lana Del Rey; Carly Rae Jepsen

BEST FEMALE: Rihanna; Katy Perry; P!nk; Taylor Swift; Nicki Minaj

BEST MALE: Justin Bieber; Kanye West; Flo Rida; Pitbull; Jay-Z

BEST POP: Justin Bieber; No Doubt; Katy Perry; Taylor Swift; Rihanna

BEST LIVE: Taylor Swift; Lady Gaga; Jay-Z & Kanye West; Green Day; Muse

BEST HIP HOP: Jay-Z & Kanye West; Nas; Rick Ross; Drake; Nicki Minaj

BEST ROCK: Linkin Park; Green Day; Muse; The Killers; Coldplay

BEST ELECTRONIC: David Guetta; Swedish House Mafia; Avicii; Skrillex; Calvin Harris

BEST ALTERNATIVE: Jack White; The Black Keys; Arctic Monkeys; Florence + The Machine; Lana Del Rey

BEST VIDEO: M.I.A./Bad Girls; Lady Gaga/Marry The Night; Katy Perry/Wide Awake; Rihanna feat. Calvin Harris/We Found Love; PSY/Gangnam Style.

(Reporting by Victoria Bryan and Maria Sheahan; editing by Mike Collett-White)

Music News Headlines – Yahoo! News

Read More..

Las guías hospitalarias no reducen las reinternaciones: estudio

NUEVA YORK (Reuters Health) – Las guías de procedimientos

para garantizarles a los pacientes hospitalarios el acceso a

servicios de calidad también apuntan a reducir la necesidad de

reinternaciones, pero un nuevo estudio sugiere que esa relación

casi no existiría.

“La idea era que al aumentar la calidad de la atención

mejorarían los resultados”, indicó la autora principal del

estudio, la doctora Michaela S. Stefan, del Centro Médico

Baystate, Massachussetts.

Para controlar los costos, los hospitales y el Gobierno

federal intentaron reducir la cantidad de reinternaciones dentro

de los 30 días posteriores al alta médica.

Desde octubre, la tasa de reinternación es uno de los

factores que evalúan los Centros para los Servicios de Medicare

y Medicaid (CMS, por su sigla en inglés) para autorizar los

reintegros.

El equipo de Stefan halló que, en realidad, uno de cada

cuatro pacientes es reinternado a los 30 días del alta y se

estima que esas reinternaciones espontáneas le costaron 17.600

millones de dólares a Medicare en el 2004 (CMS publica la

información en http://1.usa.gov/Z7TeXy).

Uno de los enfoques para reducir las reinternaciones es la

elaboración de guías de calidad de la atención de cada

enfermedad, como los infartos o la neumonía.

Un estudio reciente había sugerido la existencia de muchos

factores que los hospitales no pueden controlar y hacen que un

paciente necesite volver al hospital, como la incapacidad de un

paciente de adherir a un tratamiento en el hogar o concurrir a

las consultas de control (ver noticia de Reuters Health del 19

de octubre del 2012).

Ahora, el equipo de Stefan analizó una base de datos del

2007 de los pacientes de Medicare, el seguro de salud

estadounidense para los adultos mayores, para conocer los

resultados con los tratamientos de infartos, insuficiencia

cardíaca o neumonía, y con las cirugías estomacales, cardíacas y

ortopédicas en miles de hospitales del país.

Por ejemplo: 2.773 hospitales atendieron a 322.668 personas

con insuficiencia cardíaca durante el período estudiado y 2.940

hospitales trataron 328.830 casos de neumonía.

Cada hospital recibió un puntaje de entre 0 y 100 por

ciento, según la cantidad de pacientes atendidos con los

tratamientos recomendados para cada caso. Eso, para los

pacientes con infarto, incluiría una aspirina al llegar al

hospital o, si corresponde, orientación para dejar de fumar

antes del alta, mientras que en los pacientes con neumonía

significaría la indicación de los antibióticos adecuados y la

verificación de la vacunación contra la influenza, entre otros

puntos.

El 96 por ciento de los 117.514 pacientes con infarto

recibió algunos de los tratamientos recomendados. Sólo el 88 por

ciento recibió todos los tratamientos adecuados. Y un 80 por

ciento de los pacientes operados del estómago accedió a los

tratamientos recomendados, aunque apenas el 46 por ciento

recibió todos esos tratamientos.

Luego, el equipo observó que los hospitales con los puntajes

más altos por cumplir las guías no tenían una cantidad

“significativamente” menor de reinternaciones que los centros

con los puntajes más bajos.

“Aun si la relación era estadísticamente significativa, las

diferencias en las tasas de reinternación eran pequeñas”, afirma

el equipo en Journal of General Internal Medicine.

Para los autores, algunas explicaciones posibles de esa

ausencia de asociación serían que las guías “influyen poco en el

riesgo de reinternación” o son demasiado amplias.

Aun así, Stefan opinó que es información que los pacientes

deben recibir. “Es importante conocer que el sitio Hospital

Compare existe. Desafortunadamente, la población lo usa poco.”

FUENTE: Journal of General Internal Medicine, online 16 de

octubre del 2012.

Seniors/Aging News Headlines – Yahoo! News

Read More..

CIA chief admits affair, resigns

CIA Director David Petraeus resigned his post on Friday, confessing to having shown "extremely poor judgment by engaging in an extramarital affair." The former Army general rocketed to global prominence as the man in charge of the "surge" in Iraq and later the commander of American forces in Afghanistan.

President Barack Obama said Petraeus had led the Central Intelligence Agency "with characteristic intellectual rigor, dedication and patriotism."

"I am completely confident that the CIA will continue to thrive and carry out its essential mission, and I have the utmost confidence in Acting Director Michael Morell and the men and women of the CIA who work every day to keep our nation safe," the president said in a written statement.

"Going forward, my thoughts and prayers are with Dave and Holly Petraeus, who has done so much to help military families through her own work. I wish them the very best at this difficult time," Obama continued.

Director of National Intelligence James Clapper issued a statement that did not specify a reason for Petraeus' departure but praised his colleague extensively.

"From his long, illustrious Army career to his leadership at the helm of CIA, Dave has redefined what it means to serve and sacrifice for one's country," said Clapper.

Petraeus went to work as CIA chief in September 2011 after heading up the war in Afghanistan. He had drawn fire in the aftermath of the Sept. 11 attack on the American compound in Benghazi, Libya. His departure comes barely a week before he was scheduled to testify about the assault in closed-door sessions with the intelligence committees of the Senate and House of Representatives. Morell was expected to take his place, congressional aides said.

Petraeus' resignation letter, quoted by several news outlets, centered on his personal behavior.

"Yesterday afternoon, I went to the White House and asked the President to be allowed, for personal reasons, to resign from my position as D/CIA. After being married for over 37 years, I showed extremely poor judgment by engaging in an extramarital affair. Such behavior is unacceptable, both as a husband and as the leader of an organization such as ours," he said. "This afternoon, the President graciously accepted my resignation."

Petraeus, 60, has been described as the father of the military's counterinsurgency doctrine. The charismatic officer had been cited as a possible future presidential or vice presidential prospect.

His wife, Holly, has worked inside the Obama administration, serving at the Consumer Financial Protection Bureau.

Arizona Sen. John McCain, the ranking Republican on the Senate Armed Services Committee and one of Petraeus' most outspoken admirers, said the general "will stand in the ranks of America's greatest military heroes."

"His inspirational leadership and his genius were directly responsible—after years of failure—for the success of the surge in Iraq," McCain said in a statement. "Our thoughts and prayers are with him and his family."

In a statement, Senate Intelligence Committee Chairwoman Dianne Feinstein, a Democrat, said, "I very much regret the resignation of David Petraeus. This is an enormous loss for our nation's intelligence community and for our country.

"I wish President Obama had not accepted this resignation, but I understand and respect the decision," Feinstein added.

Read More..

Myanmar says Obama to visit later this month

YANGON, Myanmar (AP) — President Barack Obama will make a groundbreaking visit later this month to Myanmar, an official said Thursday, following through with his policy of rapprochement to encourage democracy in the Southeast Asian nation.

The Myanmar official speaking from the capital, Naypyitaw, said Thursday that security for a visit on Nov. 18 or 19 had been prepared, but the schedule was not final. He asked not to be named because he was not authorized to give information to the media.

The official said Obama would meet with opposition leader Aung San Suu Kyi as well as government officials including reformist President Thein Sein.

It would be the first-ever visit to Myanmar by an American president. U.S. officials have not yet announced any plans for a visit, which would come less than two weeks after Obama’s election to a second term.

Obama’s administration has sought to encourage the recent democratic progress under Thein Sein by easing sanctions applied against Myanmar’s previous military regime.

Officials in nearby Thailand and Cambodia have already informally announced plans for visits by Obama that same week. Cambodia is hosting a summit meeting of the Association of Southeast Asian Nations, and Thailand is a longtime close U.S. ally.

The visit to Myanmar, also known as Burma, would be the culmination of a dramatic turnaround in relations with Washington as the country has shifted from five decades of ruinous military rule and shaken off the pariah status it had earned through its bloody suppression of democracy.

Obama’s ending of the long-standing U.S. isolation of Myanmar’s generals has played a part in coaxing them into political reforms that have unfolded with surprising speed in the past year. The U.S. has appointed a full ambassador and suspended sanctions to reward Myanmar for political prisoner releases and the election of Nobel laureate Suu Kyi to parliament.

From Myanmar’s point of view, the lifting of sanctions is essential for boosting a lagging economy that was hurt not only by sanctions that curbed exports and foreign investment, but also by what had been a protectionist, centralized approach. Thein Sein’s government has initiated major economic reforms in addition to political ones.

A procession of senior diplomats and world leaders have traveled to Myanmar, stopping both in the remote, opulent capital city, which was built by the former ruling junta, and at Suu Kyi’s dilapidated lakeside villa in the main city of Yangon, where she spent 15 years under house arrest. New Zealand announced Thursday that Prime Minister John Key would visit Myanmar after attending the regional meetings in Cambodia.

The most senior U.S. official to visit was Hillary Rodham Clinton, who last December became the first U.S. secretary of state to travel to Myanmar in 56 years.

The Obama administration regards the political changes in Myanmar as a marquee achievement in its foreign policy, and one that could dilute the influence of China in a country that has a strategic location between South and Southeast Asia, regions of growing economic importance.

But exiled Myanmar activists and human rights groups are likely to criticize an Obama visit as premature, rewarding Thein Sein before his political and economic reforms have truly taken root. The military — still dominant and implicated in rights abuses — has failed to prevent vicious outbreaks of communal violence in the west of the country that have left scores dead.

Asia News Headlines – Yahoo! News

Read More..

Exclusive: Google Ventures beefs up fund size to $300 million a year

SAN FRANCISCO (Reuters) - Google will increase the cash it allocates to its venture-capital arm to up to $300 million a year from $200 million, catapulting Google Ventures into the top echelon of corporate venture-capital funds.

Access to that sizeable checkbook means Google Ventures will be able to invest in more later-stage financing rounds, which tend to be in the tens of millions of dollars or more per investor.

It puts the firm on the same footing as more established corporate venture funds such as Intel's Intel Capital, which typically invests $300-$500 million a year.

"It puts a lot more wood behind the arrow if we need it," said Bill Maris, managing partner of Google Ventures.

Part of the rationale behind the increase is that Google Ventures is a relatively young firm, founded in 2009. Some of the companies it backed two or three years ago are now at later stages, potentially requiring larger cash infusions to grow further.

Google Ventures has taken an eclectic approach, investing in a broad spectrum of companies ranging from medicine to clean power to coupon companies.

Every year, it typically funds 40-50 "seed-stage" deals where it invests $250,000 or less in a company, and perhaps around 15 deals where it invests up to $10 million, Maris said. It aims to complete one or two deals annually in the $20-$50 million range, Maris said.

LACKING SUPERSTARS

Some of its investments include Nest, a smart-thermostat company; Foundation Medicine, which applies genomic analysis to cancer care; Relay Rides, a carsharing service; and smart-grid company Silver Spring Networks. Last year, its portfolio company HomeAway raised $216 million in an initial public offering.

Still, Google Ventures lacks superstar companies such as microblogging service Twitter or online bulletin-board company Pinterest. The firm's recent hiring of high-profile entrepreneur Kevin Rose as a partner could help attract higher-profile deals.

Soon it could have even more cash to play around with. "Larry has repeatedly asked me: 'What do you think you could do with a billion a year?'" said Maris, referring to Google chief executive Larry Page.

(Editing by Muralikumar Anantharaman)

Read More..

“Dancing” co-host Brooke Burke has thyroid cancer

LOS ANGELES (Reuters) – “Dancing with the Stars” co-host Brooke Burke said on Thursday that she has been diagnosed with thyroid cancer and will need surgery.

The television presenter and model said in a three-minute video posted on the website Modernmom.com that she will need her thyroid removed.

“I need to have thyroid surgery and a thyroidectomy, which means I’m going to have a nice, big scar right here on neck,” Burke said, drawing a finger across her throat.

Burke, a former winner of ABC’s celebrity ballroom dancing competition, said she had a biopsy in July, but it had taken her months to go public with the results.

“I’m ready to deal with it, and I’m going to be fine,” she said.

There was no word on when the surgery would take place, but Burke’s publicist said her work schedule for “Dancing with the Stars” would not be affected.

Burke, 47, said in July that her doctor suggested she undergo a thyroid ultrasound after he felt a lump in her neck during a routine physical.

The thyroid is a gland in the neck that produces hormones that regulate vital body functions, such as heart rate and blood pressure.

Burke’s co-host Tom Bergeron said on Thursday during an appearance on the CBS chat show “The Talk” that he had known about her condition for several months. “We are all there with her,” he said.

“I’ve known about this for a few months … I have had experience with this in my family. You never want to hear the word cancer. But thyroid cancer is one of the most treatable cancers. It has an incredibly high success rate,” he said.

(Reporting By Eric Kelsey; Editing by Jill Serjeant)

Celebrity News Headlines – Yahoo! News

Read More..

UK’s NICE rejects Novartis asthma drug in change of tack

LONDON (Reuters) – Britain‘s health cost-effectiveness watchdog NICE plans to recommend against the use of Novartis‘s severe asthma drug Xolair, or omalizumab, after earlier endorsing it for adults only.

The National Institute for Health and Clinical Excellence (NICE), which decides if medicines should be given on the state health service, said on Friday it had changed its mind in the light of evolving clinical evidence.

“After considering new evidence that has become available since the original guidance was published – particularly new mortality data – the NICE draft guidance does not recommend omalizumab for either adults or children,” NICE said.

New dosing recommendations for the drug had also changed its cost-effectiveness, the agency added.

The revised recommendation against using the drug is still at the review stage and NICE said it was now up to Novartis and other interested parties to respond to its concerns.

(Reporting by Ben Hirschler; Editing by Elaine Hardcastle)

Diseases/Conditions News Headlines – Yahoo! News

Read More..

Boehner: Raising tax rates 'unacceptable'

Raising tax rates is "unacceptable" to House Speaker John Boehner as he prepares to open negotiations on the looming "fiscal cliff" with the president and congressional Democrats, he told "World News" anchor Diane Sawyer today in an exclusive interview.

"Raising tax rates is unacceptable," Boehner, R-Ohio, said in his first broadcast interview since the election Tuesday.

"Frankly, it couldn't even pass the House. I'm not sure it could pass the Senate."

That stance could set up a real showdown with the White House given that the president has said he would veto any deal that does not allow tax cuts for the rich to expire. But the speaker said that Republicans would put new tax revenue on the table as leaders work toward a deal.

Get Full 2012 Election Results

Read More on 2012 Exit Polls

"I would do that if the president was serious about solving our spending problem and trying to secure our entitlement programs," Boehner said. "If you're increasing taxes on small-business people, it's the wrong approach."

Nevertheless, Boehner added that he is at least willing to listen to the president's proposals, even if they clash with his party's principles.

"Of course, we'll talk about it. We talk about all kinds of things we may disagree on," Boehner said. "I'm the most reasonable, responsible person here in Washington. The president knows it. He knows that he and I can work together. The election's over. Now it's time to get to work."

John Boehner: 'Obamacare is the Law of the Land' Watch Video

Boehner: 'We Don't Have a Tea Party Caucus' Watch Video

John Boehner: There's a Mandate to Work Together Watch Video

The fiscal cliff is a mix of tax increases and spending cuts set to take effect at the end of the year that could sink the economy back into recession. Boehner told Sawyer he imagines that negotiations on a bipartisan deal will begin soon, although he did not reveal whether any talks had already been scheduled.

Still, he said he hoped the framework of a deal could be completed by the end of the year in order to direct the next Congress to work out the details.

"The American people elected new representatives," he said. "They're the ones who ought to be the ones to do this.

"There are things that we can do in the lame duck to avert the fiscal crisis, but we want to do this the right way. We don't want to rush through this in the next two to three weeks. And what do you get? You can't rewrite the tax code in the next two or three weeks. And, so, there's a lot of possibilities in terms of how we proceed, and I'm confident that we can."

Boehner also said he welcomes back Rep. Paul Ryan, whose profile has exploded since he was chosen by Mitt Romney as the vice presidential nominee. Ryan won re-election to his House seat in Wisconsin at the same time he lost the vice presidency, but Boehner demurred when asked whether his place on the presidential ticket would increase his leadership profile.

"Because he ran for the vice presidency, is he the leader of the Republican party now?" Sawyer asked.

"Oh, I wouldn't think so. Paul Ryan's a policy wonk," Boehner said. "He's involved in the cause of trying to bring us pro-growth economic agendas for America and making sure that we're doing this in a fiscally responsible way.

"I'm glad that Paul Ryan's coming back to the Congress. I would expect he would continue as chairman of the Budget Committee," he said.

"Probably nobody in the Congress knows more about pro-growth economic policies other than Paul Ryan. I don't think there's many people in the Congress who understand the entitlement crisis that we're facing more than Paul Ryan. I think he'll be an important voice in this discussion and in this debate."

Boehner also said that once he saw that Mitt Romney would lose the race for the White House, he went to sleep at about 11:15 p.m. on election night with the realization that he would wake up to divided government, but still "slept like a baby."

"I may not like the five cards that have been dealt to me, but those are the cards I've got in my hand, and my job on behalf of the American people is to find a way to vote with my Democratic colleagues and a Democratic president to solve America's problems," he said. "If there was one mandate that came out of the election, it was find a way to work together to address our problems."

Sawyer asked the speaker whether Romney should take responsibility for those election results, but Boehner said he is proud of his campaign.

Read More..

Merkel says Germany, Britain must work together on EU

LONDON (Reuters) – Germany and Britain must cooperate to work round their differences on the European Union‘s long-term spending plans, German Chancellor Angela Merkel said on Wednesday.

“Despite differences that we have it is very important for me that the UK and Germany work together,” Merkel said through a translator before a meeting in London with Prime Minister David Cameron to discuss the EU‘s 2014-2020 budget.

“We always have to do something that will stand up to public opinion back home. Not all of the expenditure that has been earmarked has been used with great efficiency … We need to address that,” she said.

EU leaders meet in Brussels on November 22-23 to try to secure a seven-year budget for the 27-nation bloc amid signs of differences of opinion over what action should be taken.

(Reporting by Peter Griffiths; Editing by Andrew Osborn)

Europe News Headlines – Yahoo! News

Read More..

Apple slides to five-month low, uncertainty grows

'},"otherParams":{"t_e":1,".intl":"US"},"events":{"fetch":{lv:2,"sp":"97570179","ps":"LREC,MON","npv":true,"bg":"#FFFFFF","em":escape('{"site-attribute":"_id=\'6fc6e2e9-b163-3060-b8dd-69df1e64d440\' sensitivity=\'0\' rs=\'lmsid:a0770000002GZ5iAAG\' ctype=\'fn_news;News\' ctopid=\'1499989;1550500;2299500;1507989;1545500;1506989;1542500;1550000;1507489;1577000\' can_suppress_ugc=\'1\' content=\'no_expandable;ajax_cert_expandable;\' ADSSA"}'),"em_orig":escape('{"site-attribute":"_id=\'6fc6e2e9-b163-3060-b8dd-69df1e64d440\' sensitivity=\'0\' rs=\'lmsid:a0770000002GZ5iAAG\' ctype=\'fn_news;News\' ctopid=\'1499989;1550500;2299500;1507989;1545500;1506989;1542500;1550000;1507489;1577000\' can_suppress_ugc=\'1\' content=\'no_expandable;ajax_cert_expandable;\' ADSSA"}')}}};var _createNodes=function(){var nIds=_conf.nodeIds;for(var i in nIds){var nId=nIds[i];var dId=_conf.destinationMap[nIds[i].replace("yom-","")];n=Y.one("#"+nId);if(n)var center=n.one("center");var node=Y.one("#"+dId);var nodeHTML;if(center && !node){nodeHTML=_conf.nodes[nId];center.insert(nodeHTML);};};};var _prepareNodes=function(){var nIds=_conf.nodeIds;for(var i in nIds){var nId=nIds[i];var dId=_conf.destinationMap[nIds[i].replace("yom-ad-","")];n=Y.one("#"+nId);if(n)var center=n.one("center");var node=Y.one("#"+dId);if(center && node){center.set("innerHTML","");center.insert(node);node.setStyle("display","block");};};};var _darla;var _config=function(){if(YAHOO.ads.darla){_darla = YAHOO.ads.darla;_createNodes();};};var _fetch=function(spaceid,adssa,ps){
if (typeof(ps)!='undefined')
_conf.events.fetch.ps = ps;if(typeof spaceid != "undefined") _conf.events.fetch.sp=spaceid;adssa = (typeof adssa != "undefined" && adssa != null) ? escape(adssa.replace(/\"/g, "'")) : "";_conf.events.fetch.em=_conf.events.fetch.em_orig.replace("ADSSA", adssa);if(_darla){_prepareNodes();_darla.setConfig(_conf);_darla.event("fetch");};};Y.on("domready", function(){_config();});;var that={"fetch":_fetch,"getNodes":_conf.nodes,"getConf":_conf};return that;}();/* Backwards compatibility - Assigning the latest instance to the main fetch function */YUI.PhotoAdsDarla.fetch=YUI.PhotoAdsDarla.photoslightboxdarla.fetch;
});
Y.later(10, this, function() {YAHOO.namespace('Media.Social').Lightbox = {};
});
Y.later(10, this, function() {Y.Media.Article.init();
});
Y.later(10, this, function() {new Y.Media.AuthorBadge();
});
Y.later(10, this, function() {new Y.Media.Branding();
});
Y.later(10, this, function() {Y.on("load", function () {
YUI.namespace("Media.SocialButtons");

var instances = YUI.Media.SocialButtons.instances || [],
globalConf = YAHOO.Media.SocialButtons.conf || {},
vplContainers = [];

Y.all(".ymsb").each(function (node) {
var id = node.get("id"),
conf = YAHOO.Media.SocialButtons.configs[id],
instance;

if (conf) {
instance = new Y.SocialButtons({
srcNode: node,
config: Y.merge(globalConf, conf.config || {}),
contentMetadata: conf.content || {},
tracking: conf.tracking || {}
});
vplContainers.push(
{
selector: "#" + id,
callback: function(node) { instance.render(); instance = conf = id = null; }
});

if (conf.config && conf.config.dynamic) {
instances.push(instance);
}
}
});

Y.Global.Media.ViewportLoader.addContainers(vplContainers);
YUI.Media.SocialButtons.instances = instances;
});
});
Y.later(10, this, function() {if (!Y.Media) {

return;

}

Y.Media.boba_lightbox_module_targets = Y.Media.boba_lightbox_module_targets || {};

Y.Media.boba_lightbox_module_configs = Y.Media.boba_lightbox_module_configs || {};

Y.Media.boba_lightbox_module_dataset = Y.Media.boba_lightbox_module_dataset || {};

Y.Media.boba_lightbox_module_whitelist = Y.Media.boba_lightbox_module_whitelist || {};


Y.Media.boba_lightbox_module_targets['lightboxfb11463e5e719400ca18bc98b9778ce3'] = {"lightboxId":"cdb195a8f28db8cb968141f778323a6b","pivotId":"94bf589f-afdb-3d01-8984-fc68fffb427d"};


Y.Media.boba_lightbox_module_dataset['cdb195a8f28db8cb968141f778323a6b'] = {"spaceid":"97570179","total":1,"photoby":"Photo By","xhrtype":"slideshow","videoconf":{"autoplay":true,"continuousPlay":true,"mute":false,"volume":"1.00","lang":"en-US","site":"news","region":"US","jurisdiction":"US","YVAP":{"accountId":"145","playContext":"default"},"pageSpaceId":"97570179","comscoreC4":"US News","comscoreC6":"","showEmbedCode":true,"showShareUrl":true,"expName":"MediaArticleRelatedLightbox","expType":"inline","apiEnv":"prod"},"slideshow_id":null,"slideshow_title":null,"slideshow_title_baked_html":null,"slideshow_desc":null,"slideshow_rev":null,"slideshow_plink_vita":null,"photos":[{"type":"image","url":"http:\/\/l2.yimg.com\/bt\/api\/res\/1.2\/o7g52ZfQO2z79PRDnwNuug--\/YXBwaWQ9eW5ld3M7Zmk9aW5zZXQ7aD0zMTI7cT03OTt3PTQ1MA--\/http:\/\/media.zenfs.com\/en_us\/News\/Reuters\/2012-11-07T221353Z_4_CBRE8A61BIA00_RTROPTP_2_USA.JPG","width":450,"height":312,"uuid":"94bf589f-afdb-3d01-8984-fc68fffb427d","caption":"The Apple logo hangs in a glass enclosure above the 5th Ave Apple Store in New York, September 20, 2012. Apple's iPhone 5 goes on sale tomorrow. REUTERS\/Lucas Jackson","captionBakedHtml":"

The Apple logo hangs in a glass enclosure above the 5th Ave Apple Store in New York, September 20, 2012. Apple's iPhone 5 goes on sale tomorrow. REUTERS\/Lucas Jackson","date":"Wed, Nov 7, 2012 5:38 PM EST","credit":"Reuters","byline":"LUCAS JACKSON","provider":"Reuters","photo_title":"The Apple logo hangs in a glass enclosure above the 5th Ave Apple Store in New York","pivot_alias_id":"apple-logo-hangs-glass-enclosure-above-5th-ave-photo-170604491","plink":"\/photos\/apple-logo-hangs-glass-enclosure-above-5th-ave-photo-170604491.html","plink_vita":"http:\/\/news.yahoo.com\/photos\/apple-logo-hangs-glass-enclosure-above-5th-ave-photo-170604491.html","srchtrm":"The Apple logo hangs in a glass enclosure above the 5th Ave Apple Store in New York","revsp":"","rev":"d8572ae0-292b-11e2-9df6-ca0851fb565a","surl":"http:\/\/l2.yimg.com\/bt\/api\/res\/1.2\/SFfjn7JLYfdmmNshb8PUtA--\/YXBwaWQ9eW5ld3M7Zmk9aW5zZXQ7aD01NjtxPTc5O3c9ODE-\/http:\/\/media.zenfs.com\/en_us\/News\/Reuters\/2012-11-07T221353Z_4_CBRE8A61BIA00_RTROPTP_2_USA.JPG","swidth":81,"sheight":56}]};

Y.Media.boba_lightbox_module_configs['cdb195a8f28db8cb968141f778323a6b'] = {"spaceid":"97570179","ult_pt":"story-lightbox","darla_id":"","images_total":0,"xhr_url":"\/_xhr\/related-article\/lightbox\/?id=6fc6e2e9-b163-3060-b8dd-69df1e64d440","xhr_count":20,"autoplay_if_first_item_is_video":true};
});
Y.later(10, this, function() {new Y.Media.RelatedArticle({count:"2",start:"1",
mod_total:"10", total:"0",
content_id:"6fc6e2e9-b163-3060-b8dd-69df1e64d440",
spaceid:"97570179",
related_count:"-1"
});
});
Y.later(10, this, function() {(function(d){
d.getElementsByTagName('head')[0].appendChild(d.createElement('script')).src='http://d.yimg.com/oq/js/csc_news-en-US-core.js';
})(document);
});
Y.later(10, this, function() {
if(!("Media" in YAHOO)){YAHOO.Media = {};}
if(!("ugcrate" in YAHOO.Media)){YAHOO.Media.ugcrate = {};}
if(!("Media" in Y)){Y.namespace("Media");}
YAHOO.Media.ugcrate.ratings_5edd788e9527897897ec94abed6516ae = new Y.Media.UgcRate({"context_id":"09a9faf4-1bcc-43ad-ac6a-bd9f23f9f173","sCrumb":"","containerId":"yom-sentimentrate-5edd788e9527897897ec94abed6516ae","rateDimensions":"d1","appLang":"en-US","sUltSId":"97570179","sUltProperty":"news-en-US","sUltCampaign":"","sUltPlatform":"ugcwidgets","sUltIntl":"US","sUltLang":"en-US","selfPageUrl":"http:\/\/news.yahoo.com\/apples-shares-slide-4-percent-five-month-low-170604771--sector.html?_esi=0","artContentId":"6fc6e2e9-b163-3060-b8dd-69df1e64d440","sUltQstnTxt":"How confident are you that your privacy is being protected when you browse the internet?","artContentTitle":"Apple slides to five-month low, uncertainty grows","artContentDesc":"SAN FRANCISCO\/NEW YORK (Reuters) - Shares of Apple Inc slid almost 4 percent on Wednesday to a five-month low as investors grew more uncertain about its ability to fend off unprecedented competition and untangle a snarled iPhone 5 supply chain. Apple\\'s slide outpaced the S&P 500\\'s drop of about 2.4 percent the day after the U.S. election, putting the world\\'s most valuable technology company into bearish territory. Long a mainstay of many fund portfolios, Apple on Wednesday lost 20 percent - $130 billion of its market value - since hitting a record high in September. ...","sUltBucketId":"test1","sUltSection":"sentirating","sUltBeaconUrl":"","sUltRecordPageviews":"1","sUltBeaconEnable":"1","serviceUrl":"\/_xhr","publisherContextId":"","propertyId":"2fcd79b5-b3a3-333e-b98e-722536a6698f","configurationId":"435db9ee-c55e-3766-b20d-c8ad3ff889d1","graphId":"","labelLeft":"Not at all confident","labelRight":"Completely confident","labelMiddle":"","itemimg":"http:\/\/l.yimg.com\/a\/i\/ww\/met\/yahoo_logo_us_061509.png","selfURI":"","aggregateRatingCount":"44824","aggregateReviewCount":"0","leftBlocksNum":"42468","rightBlocksNum":"2356","leftBlocksPerCent":"95","rightBlocksPerCent":"5","ugcrate_apihost":"api01-us.ugcl.yahoo.com:4080","publisher_id":"news-en-US","yca_cert":"yahoo.ugccloud.app.trusted_proxies","timeout_write":"5000","through_proxy":"false","optionStats":"{\"s1\":33898,\"s2\":3644,\"s3\":1666,\"s4\":1659,\"s5\":1601,\"s6\":2356,\"s7\":0,\"s8\":0,\"s9\":0,\"s10\":0}","l10N":"{\"FIRST_TO_READ\":\"You are first to read this. Share your feelings and start a conversation.\",\"SHARE_YOUR_FEELINGS\":\"You too can share your feelings and start a conversation!\",\"HOW_YOUR_FRIENDS_THINK\":\"Thank you for sharing your feeling on this article!\",\"PRE_SHARE_MSG\":\"Your Facebook friends on Yahoo! can see how you responded. To share your response on Facebook, click on the Facebook share option.\",\"START_THE_CONVERSATION\":\"Start the Conversation\",\"THANKS_FOR_SHARING\":\"Sure, that's how you feel... But what do your friends think?\",\"POLL_HEADER\":\"SOCIAL SENTIMENT\",\"SERVER_ERROR\":\"Oops there seems to be some error, please try again later\",\"LOADING\":\"Loading...\",\"SHARE_AFTER_COMMENT\":\"Your response has been shared on Facebook.\",\"UNDO\":\"Undo\",\"UNIT_PEOPLE\":\"People\",\"NUM_PEOPLE_DISAGREE\":\"disagree with your opinion.\",\"READ_MORE_TEXT\":\"Read what they have to say.\",\"SLIDER_THUMB_WORDING_BEFORE_VOTING\":\"WHAT DO YOU THINK?\",\"SLIDER_THUMB_WORDING_VERB_BEFORE_VOTING\":\"DRAG\",\"SLIDER_THUMB_WORDING_THANKS_VOTING\":\"Thanks for voting\",\"NUM_PEOPLE_ANSWERED\":\" 44,824 people have responded\",\"ONE_PERSON_ANSWERED\":\" 1 person has responded. Your response will be seen by your Facebook friends on Yahoo!\",\"TWO_PEOPLE_ANSWERED\":\" 2 people have responded. Your response will be seen by your Facebook friends on Yahoo!\",\"NUM_PEOPLE_ANSWERED_AND_SHARED\":\" 44,824 people have responded. Your response will be seen by your Facebook friends on Yahoo!\",\"NUM_PEOPLE_RATED__s1\":33898,\"NUM_PEOPLE_RATED__s2\":3644,\"NUM_PEOPLE_RATED__s3\":1666,\"NUM_PEOPLE_RATED__s4\":1659,\"NUM_PEOPLE_RATED__s5\":1601,\"NUM_PEOPLE_RATED__s6\":2356,\"NUM_PEOPLE_RATED__s7\":0,\"NUM_PEOPLE_RATED__s8\":0,\"NUM_PEOPLE_RATED__s9\":0,\"NUM_PEOPLE_RATED__s10\":0}","fbconfig":"{\"message\":\"undefined\",\"name\":\"undefined\",\"link\":\"\",\"source\":\"\",\"picture\":\"http:\\\/\\\/l.yimg.com\\\/a\\\/i\\\/ww\\\/news\\\/2011\\\/09\\\/27\\\/yahoo-tc.jpg\",\"description\":\"\",\"captionLeft\":\"undefined\",\"captionRight\":\"undefined\",\"app_id\":\"196660913708276\",\"redirect_uri\":\"\\\/_xhr\\\/ugcratefbredirect\\\/\"}","template_id":"LONG_SLIDER_SOUTH","obj_id":"ratings_5edd788e9527897897ec94abed6516ae","opt_count":"6","opt_color1":"","opt_color2":"","template_html":"

Read More..

Death of the cassette tape much exaggerated

LONDON (Reuters) – The widening gap between the amount of data the world produces and our capacity to store it is giving a new lease of life to the humble cassette tape.

Although consumers have abandoned the audio cassette in favor of the ubiquitous iPod, organizations with large amounts of data, from patient records to capacity-hungry video archives, have continued to use tape as a cheap and secure storage medium.

Researchers at IBM are trying to keep this 60-year old technology relevant for at least the next decade and they are getting help from rising energy costs, which are forcing companies to look for cheaper alternatives to stacks of power-hungry hard drives.

Evangelos Eleftheriou and his colleagues at IBM Research in Zurich, Switzerland, have developed a cassette just 10 cm by 10cm by 2cm that can hold about 35 terabytes of data, the equivalent of a library with 400 kilometers of bookshelves.

“It is really the greenest storage technology,” Eleftheriou told Reuters. “Tape at rest, consumes literally zero power.”

Unlike hard drive storage devices, which have to be on continuously, tape systems only consume power when data is being read or recorded, giving them a carbon footprint a fraction that of their disc-based counterparts.

Latency is the biggest disadvantage. Tapes have to be retrieved, usually by a robotic selector, and then loaded into a reading device.

But for much of the world’s archived data, access time is not critical. From legal archives and company records kept to comply with legislation like the Sarbanes Oxley Act in the United States, to data on traffic flow and weather patterns, keeping secure copies is more important than instant access.

“If you have big data then you have really big backups,” said Eleftheriou.

This is borne out by an estimate from consultancy Coughlin Associates that about 400 exabytes, equal to 20 million times the content of U.S. Library of Congress, is currently stored on tape.

The new IBM cassette, originally developed with Fuji Film, packs about 29.5 billion bits on a square inch of tape using a coating made from the chemical compound barium ferrite, which maximizes so-called linear density – the amount of data that can be squeezed onto a length of the tape.

The other limitation is the number of tracks that can be laid down and the researchers have developed novel nanopositioning technologies that can position the read and write heads with an accuracy of 10 to 15 billionths of a meter.

SERIOUSLY BIG DATA

Eleftheriou and his team believe they can increase the storage capacity to 100 billion bits per square inch and they hope this will make tape storage a contender for one of the world’s biggest data collection projects – the huge radio telescope known as the Square Kilometer Array (SKA).

In just over 10 years the SKA will start scanning the skies from two remote sites in South Africa and Australia, and it will generate 10 times the data traffic of the global internet.

“There’s going to be a lot of data pouring out of what is essentially a giant computer with a few bits of metal (the dishes and the antennae) on the ends,” said Andy Faulkner, an astrophysicist at Cambridge University and one of the project engineers on the SKA.

Faulkner said there has been quite a shift towards using hard drives in astronomy in recent years because their capacity has grown so far and fast, but the SKA will be a different kettle of fish, not least because of the vast amount of data it will generate and the restrictions on power usage from its remote location.

“In truth, nobody knows just yet what we will be using given the 10-year time frame but tape storage is very interesting because you don’t necessarily need real time access to everything.”

(Editing by Jon Hemming)

Music News Headlines – Yahoo! News

Read More..

Organ on a chip? Scientists test drugs on tiny, artificial lung

CHICAGO (Reuters) – U.S. researchers have begun testing drugs using a microchip lined with living cells that replicates many of the features of a human lung, a technology that may one day help improve drug testing and reduce researchers’ dependence on animal studies.

In 2010, researchers at Harvard’s Wyss Institute for Biologically Inspired Engineering developed the so-called lung-on-a-chip technology that mimics the function of air sacs called alveoli, which transfer oxygen through a thin membrane from the lung to the blood.

For drug companies, the technology offers a way to better predict how drugs will work in people, ultimately reducing the cost of drug development by identifying problems before drugs are tested in clinical trials.

“Major pharmaceutical companies spend a lot of time and a huge amount of money on cell cultures and animal testing to develop new drugs, but these methods often fail to predict the effects of these agents when they reach humans,” Dr. Donald Ingber, whose study was published on Wednesday in Science Translational Medicine, said in a statement.

Now the Wyss team is putting its artificial lung to the test, using the device to recreate pulmonary edema, a condition that causes fluid to leak into the air sacs of the lungs, and then treating it with an experimental drug from GlaxoSmithKline.

The device, which is about the size of a memory stick, is made of a flexible polymer that contains hollow channels.

These channels are divided by a thin, permeable membrane lined on one side with human lung cells and on the other with tiny blood vessel or capillary cells that are bathed in fluid to simulate blood flow. A vacuum is applied to recreate the way human tissue stretches during breathing.

For the study, the team treated the device with interleukin-2 or IL-2, a cancer drug that can cause pulmonary edema, a deadly condition in which the lungs fill with fluid and blood forms clots.

When injected into the blood channel of the device, the drug caused fluid to start leaking across the membrane, reducing the amount of volume of air in the other channel. Blood plasma crossed into the air channels and started to clot.

Dr. Geraldine Hamilton, co-author on the paper and the senior lead for the organs on chips program at Wyss, said the study is “providing us with a very exciting proof of concept for our ability to use organs on chips to create human disease models.”

When the team turned on the vacuum to simulate breathing, fluid leakage increased, suggesting that breathing may make the condition worse.

“We learned more about the mechanisms by which this happens. Than really wouldn’t have been possible through an animal model,” Hamilton said.

The team next used their model to test a new class of drug being developed by GlaxoSmithKline called a TRPV4 channel blocker. They found that treating the tissues in the device with the Glaxo drug before exposing it to IL-2 prevented blood vessel leakage in the device.

To confirm this finding, Kevin Thorneloe, a scientist at GlaxoSmithKline, did a parallel study in which he tested the drug in the lungs of rodents and dogs with pulmonary edema caused by heart failure and found the drug improved lung function and reduced leakage, consistent with the chip finding.

“These findings suggest that TRPV4 blockers could be used to limit pulmonary edema in patients with heart or lung disease, and were an important step toward validating the lung on a chip model,” said Thorneloe, whose companion study was published in the same journal.

“This technology is still in its early stages of development,” he said, noting that several additional studies will be needed to further validate the chip device.

Although initially, such devices will be used to support early research seeking to get a better understanding of disease at the molecular level, Thorneloe said over time, they could be used to quickly study the impact of several drugs on lung function.

In July, Wyss entered a $ 37 million agreement with the U.S. defense department to help develop 10 engineered organs, all linked into one system.

The idea is to replicate a human body on a chip, which could be used to rapidly assess responses to new drugs and potential chemical threats.

Donna Dambach, a pre-clinical safety scientist at Roche’s Genentech unit, said she thinks drug companies will be quick to adopt these technologies for their own internal decision-making.

But Dambach said it will likely take much longer for drug companies to replace animal models used for regulatory approval with these engineered organs.

“I think everyone would love that, but animals are complex, like human beings, and we really have to make certain that we’re at least predicting some level of that complexity in these systems.”

(Reporting by Julie Steenhuysen; Editing by Eric Walsh)

Medications/Drugs News Headlines – Yahoo! News

Read More..

Latino groups to Obama: You owe us

Voters in a polling place in East Los Angeles on Tuesday (David McNew/Getty Images)

In initially off-the-record comments to the Des Moines Register's editors in October, President Barack Obama said that if he won re-election, he would owe it to Latinos.

"Should I win a second term," Obama said, "a big reason I will win a second term is because the Republican nominee and the Republican Party have so alienated the fastest-growing demographic group in the country, the Latino community."

Exit polls show the president's prediction was on the mark.

The national exit poll estimated that about 10 percent of those who voted in the presidential election identified as Hispanic, marking Latinos' highest-ever share of the electorate. Latinos backed Obama over challenger Mitt Romney a resounding 71 to 27 percent.

Gary Segura, a pollster for Latino Decisions and a professor at Stanford University, told reporters on Wednesday that he believes the exit poll understated Latinos' support for Obama by 4 points, and that the president actually won 75 percent of their vote.

Segura estimates that Latinos gave Obama an extra 2.3 percentage points in the popular vote. If Romney had managed to nab just 35 percent of Latinos, he would have won the popular vote, Segura said. (President George W. Bush captured at least that share of Latinos in 2000 and 2004, showing Republicans are backsliding with the group.)

Leaders of immigrant rights and Latino groups told reporters in a conference call on Wednesday that Obama owes his second term to Latino voters, and should repay them by passing comprehensive immigration reform. Obama promised to pass a law legalizing many of the estimated 11 million illegal immigrants in the country while he campaigned four years ago, and he's been chastised by Latino leaders for breaking his promise.

"Obama is going to return to the White House more energized to take these issues seriously," said Ben Monterroso, the director of Mi Familia Vota, a national organization that encourages Latinos to vote.

Eliseo Medina, secretary-treasurer of the Service Employees International Union, said Latino voters had sent a message to Obama. "We expect leadership on comprehensive immigration reform in 2013," he said. "To both sides we say: 'No more excuses.'"

The heavy pro-Obama Latino vote also sends a message to the Republican Party, which needs to make inroads in the fast-growing Hispanic community to survive. Ana Navarro, a Miami-based Republican political strategist who had warned Republicans to take a softer tone on immigration if they wanted to win the election, wrote on Twitter that gaining only 27 percent of the Latino vote is a "disgrace."

Most Latino voters said in the Latino Decisions poll that the most important issues to them in this election were the economy and jobs. Thirty-five percent of the voters listed immigration reform as their key issue.

"Our party needs to realize that it's too old and too white and too male, and it needs to figure out how to catch up with the demographics of the country before it's too late," Al Cardenas, the head of the American Conservative Union, told Politico. "Our party needs a lot of work to do if we expect to be competitive in the near future."

Read More..